The Ruins of Sanctity are paired with the Prairie Entrance, both of which can be accessed from the fourth boat. The area is very similar to the Perilous Ruins, with the exception of tougher enemies and an overcast, sometimes rainy environment.
Many of the enemies are Gnolls, with more complex fighting patterns and better equipment than those of the Perilous Ruins. Some enemies look and act similarly to the Red Gnoll Chieftain, with similar equipment and attack patterns.
The Ruins of Sanctity are also much more evolved than the Perilous Ruins in terms of traps and obstacles. One notable trap type is walls that close in on the player, pushing them into a pit or slamming them into a wall. Both do significant damage.